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2009 NOV 23 ... gene or genes implicated in the progression of a disease by "interfering" with messenger RNA. However, success in developing RNAi therapies has been elusive to date because of ...
2009 NOV 23 ... using anti-VDIPEN antibodies and chondrocyte activation with anti-S100A8 antibodies. Messenger RNA (mRNA) levels were determined in inflamed synovium using microarray analysis and ...
2009 NOV 24 ... a new piRNA cluster. piRNAs arising from tj correspond to the untranslated regions of tj messenger RNA and are sense-oriented. piRNA loading on to Piwi may occur in the cytoplasm. ...
2009 NOV 23 ... (GTPase) that plays a crucial role in the translocation of transfer RNAs (tRNAs) and messenger RNA (mRNA) during translation by the ribosome. We report a crystal structure refined to 3.6 ...
2009 NOV 24 ... transfer RNA (tRNA) for each amino acid added to the polypeptide chain, as directed by messenger RNA. Aminoacyl-tRNA is delivered to the ribosome by elongation factor Tu (EF-Tu), which ...
2009 NOV 10 ... of TRIF in changes in cardiopulmonary physiology after MV. MV significantly Increased messenger RNA expression of interleukin (IL)-1 beta in wild-type mice, but not in TRIF mutant mice. In ...
2009 NOV 23 ... 21 nucleotide long RNA molecules that affect gene expression by interacting with messenger RNAs. Unlike siRNAs, miRNAs are encoded in the human genome and are natural regulators ...
2009 NOV 16 ... cholesterol rich-diet (western diet) and angiotensin II infusion. Kinin B1 receptor messenger RNA (mRNA) expression was significantly increased in ApoE(-/-) mice after Western-type diet. ...
2009 NOV 23 ... "We exhibited for the first time a serial, sequential screening analysis of monocyte messenger RNA expression patterns in patients with multiple trauma indicating a strongly significant ...
2009 NOV 23 ... OA in the knee joints of rats. In the in vitro study, we measured the levels of messenger RNA for SOX9, aggrecan, type II collagen, type X collagen, alkaline phosphatase (AP), Indian ...
2009 NOV 10 ... fully understood. We have previously found a significant increase in the expression of messenger RNA (mRNAs) encoding extracellular basement membrane (BM) proteins of the smooth muscle ...
2009 NOV 16 ... range), in the FMR1 gene. The neurological changes are linked to the excessive FMR1 messenger RNA (mRNA), becoming toxic through a 'gain-of-function'," scientists writing in the ...
2009 NOV 16 ... in this process in vivo is unknown." "Here, we report that IPCEF1 messenger RNA (mRNA) is expressed in the dorsal root ganglions (DRGs) of adult rats. Moreover, ...
2009 NOV 23 ... ribonucleoside (AICAR). Lipoprotein lipase activity, LPL protein expression, and LPL messenger RNA (mRNA) expression were measured. Metformin increased LPL activity only in skeletal ...
2009 NOV 23 ... increased the levels of intracellular cAMP, but not Ca2+, in chondrocytes. Both messenger RNA and protein expression of various proinflammatory cytokines, collagens, matrix metal ...
2009 NOV 10 ... unknown." "The aim of this study was to evaluate the expression of Tbx22 messenger. RNA (mRNA) during palatogenesis in glucocorticoid-/alcohol-induced cleft palate in a ...
2009 NOV 17 ... Y' subtelomeric repeats. In S. castellii, RNAi mutants are viable but have excess Y' messenger RNA levels. In S. cerevisiae, introducing Dicer and Argonaute of S. castellii restores RNAi, ...
2009 NOV 9 ... by a lack of the protein Pur-alpha. This protein binds to the CGG sequences in FMR messenger RNAs (mRNA). The excessive numbers of CGG triplets found in the mutant FMRP mRNA ... binds to the CGG repeats. The next step is to find out precisely how Pur-alpha binds to RNA. This in turn could suggest ways of preventing the interactions that cause the disease. ...
2009 NOV 16 ... oblimersen in breast tumor biopsies." "Oblimersen targets Bcl-2 messenger RNA (mRNA), down-regulates Bcl-2 protein translation and enhances antitumor effects of ...
