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2009 NOV 1 ... to improve impulse conduction in nerve fibers in which the insulating layer, called myelin, has been damaged. Fampridine-SR is being developed by Acorda Therapeutics and ...
2009 NOV 23 ... allergic encephalitis, a model of organ-specific autoimmunity, oral tolerization with myelin basic protein was abrogated as well in Grail(-/-) mice. On the protein level, Grail(-/-) ...
2009 NOV 3 ... of type III beta 1a neuregulin dictate not only the myelination fate of axons but also myelin thickness." "Here we show that another neuregulin isoform, type III-beta ...
2009 NOV 23 ... Oligodendrocytes have two main functions in the spinal cord; they produce the myelin that wraps around nerve fibers to enable electrical impulse conduction and they produce ...
2009 NOV 9 ... in European Journal of Immunology (Stable silencing of the glucocorticoid receptor in myelin-specific T effector cells by retroviral delivery of shRNA: Insight into ...
2009 NOV 2 ... we observed that RAAS is up-regulated in brain lesions of MS. AT1R was induced in myelin-specific CD4(+) T cells and monocytes during autoimmune neuroinflammation. Blocking AII ...
2009 NOV 2 ... in Bochum, Germany report. "Here we study the role of the RAS in myelin-oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis ...
2009 NOV 16 ... role for CNS laminin is to promote the development of oligodendrocyte progenitors into myelin-forming oligodendrocytes via modulation of Fyn regulatory molecules." ...
2009 NOV 16 ... "The formation of oligodendrocytes (oligodendrogenesis) and myelin is regulated by several neurotrophic factors. Strategies to increase the level of these ...
2009 NOV 1 ... the experimental autoimmune encephalomyelitis (EAE) mouse model of MS." "Myelin oligodendrocyte glycoprotein-induced EAE mice received oral administration of GGA at 500 ...
2009 NOV 16 ... and intrathecal (IT) administration of human NPCs in common marmosets affected by human myelin oligodendrocyte glycoprotein 1-125-induced EAE. Treatment commenced upon the occurrence ...
2009 NOV 9 ... nuclear antigen, and heat shock protein 70 were increased, whereas neurofilament and myelin-associated glycoprotein were decreased corresponding to the severity of neurological ...
2009 NOV 9 ... shift in cytokine balance from Th1 to Th2 in the T-cell response against elements of the myelin sheath," scientists in the United States report. "In addition to the Th1 ...
2009 NOV 23 ... and the double mutant are characterized by similar levels of demyelination and aberrant myelin structures. Nevertheless, the double mutant exhibits more severe electrophysiological ...
2009 NOV 16 ... growth factor receptor-dependent intra-axonal signalling of central nervous system myelin-related axon growth inhibitory ligands," investigators in Edgbaston, the United Kingdom ...
2009 NOV 2 ... taken from three spinal cord levels and stained using Luxol Fast Blue/Cresyl Violet and myelin protein immunohistochemistry. Measurements of neuronal number and size were made for all ...
2009 NOV 9 ... also as MAC-2; Galectin-3/MAC-2) in the activation of the phagocytosis of degenerated myelin that is mediated by complement receptor-3 (known also as MAC-1; CD11b/CD18; alpha M beta ...
2009 NOV 16 ... to be an autoimmune disorder. MS symptoms result when an immune-system attack affects myelin, the protective insulation surrounding nerve fibers of the central nervous system (the ...
