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2009 OCT 6 ... weight of MPD in mice. Protein of 46-kDa detected in guinea pig liver treated with 0.1% pravastatin, a 3-hydroxy-3-methylglutaryl-CoA reductase inhibitor indicating a liver-specific ...
2009 SEP 7 ... 'No significant effect of ABCB1 haplotypes on the pharmacokinetics of fluvastatin, pravastatin, lovastatin, and rosuvastatin,' is newly published data in British Journal of Clinical ...
2009 NOV 23 ... (Gallus gallus domesticus) embryonic development, fertilized eggs were administrated pravastatin in ovo, a 3-hydroxy-3-methylglutaryl CoA reductase (HMG-CoA reductase) inhibitor, at ...
2009 OCT 19 ... in 9 genes were genotyped in 1507 post-ACS subjects randomized to atorvastatin or pravastatin." "Two polymorphisms (rs7412, rs429358) that define the epsilon 2, ...
2009 SEP 14 ... infarction (MI) and stroke." "and Findings: In the Prospective Study of Pravastatin in the Elderly at Risk (PROSPER), baseline inflammatory markers in up to 5,680 men and ...
2009 NOV 9 ... "This study investigates the effect of pravastatin on blood pressure, cardiovascular remodelling and impaired endothelial function induced ...
2009 NOV 9 ... arteries are altered in the early stage of diabetes. Such alterations and the effects of pravastatin were examined in left anterior descending coronary arteries (LAD) from Otsuka Long-Evans ...
2009 SEP 14 ... pathway. They are either lipophilic (e.g. simvastatin) or hydrophilic [e.g. pravastatin (PRV)] compounds, considered mainly for long-term treatment of hypercholesterolaemic ...
2009 OCT 5 ... unclear. We retrospectively assessed the long-term efficacy of combination therapy with pravastatin (10 mg/day) and enalapril (5 mg/day) in addition to antiarrhythmic drugs (AAD) for ...
2009 AUG 17 ... anti-HCV activity, lovastatin and fluvastatin have moderate inhibitory effects, and pravastatin is devoid of an antiviral effect. A combination of statins with interferon-alpha ...
2009 AUG 10 ... report. "Ninety high-risk coronary patients were allocated to 3 groups: pravastatin 40 mg, simvastatin 40 mg, and simvastatin 20 mg and ezetimibe 10 mg initially. If the ...
2009 NOV 16 ... doses of simvastatin (0.25 mc M), lovastatin (0.25 mc M), mevastatin (0.25 mc M), pravastatin (10 mc M), or gamma-tocotrienol (2 mc M) alone had no effect on protein prenylation or ...
2009 AUG 10 ... cycle progression. Treatment with 0.25 mc M simvastatin, lovastatin, mevastatin, 10 mc M pravastatin or 2.0 mc M gamma-tocotrienol alone had no effect, while combined treatment of ...
2009 AUG 24 ... investigated the influence of body mass index (BMI) on the inhibitory effects of pravastatin against the development of coronary atherosclerosis." "In 56 patients ...
2009 AUG 24 ... of metabolic syndrome, were untreated or treated with olmesartan 3 mg kg(-1) per day, pravastatin 30 mg kg(-1) per day or their combination for 25 weeks. Long-Evans Tokushima Otsuka rats ...
2009 OCT 19 ... studies. The amount of drug transported from the duodenum was reduced in the presence of pravastatin, a specific OATP inhibitor (1581.0 +/- 7.8 nM to 1265.0 +/- 5.5 nM)," wrote S.P. Boddu ...
2009 OCT 12 ... Surgery, Surgery Department. The researchers concluded: "Treatment with pravastatin, which down-regulates glomerular TF synthesis, prevents aPL-induced TMA in this mouse ...
2009 AUG 10 ... gene suppressed the mutant phenotypes. The hmg1-1 mutant showed hypersensitivity to pravastatin, an HMGR inhibitor, suggesting a defective HMGR activity. The mutant treated with FK506 ...
2009 NOV 16 ... of Colorado. The researchers concluded: "Furthermore, we demonstrate that pravastatin inhibition of calcific nodule formation is related to inhibition of myofibroblastic ...
