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2009 NOV 2 ... on optimizing a patient's own (autologous) dendritic cells to trigger a pathogen- or tumor-specific immune response. To address the challenge of the unique genetic profile of each ... cell-based immunotherapy that is perfectly matched to each patient's unique HIV viral burden. The presentations contained important results, including a favorable safety profile for ...
2009 NOV 23 ... and work-equipment adaptations for employees with RA were calculated. Costs of the tumor necrosis factor antagonist adalimumab were compared with those of other RA treatments. ... (57%), absenteeism/disability (21%) and Job turnover (21%). RA imposes a large financial burden on employers, predominantly owing to lost productivity," wrote H. Birnbaum and ...
2009 NOV 23 ... adverse social environment is associated with altered mammary gland gene expression and tumor growth," wrote J.B. Williams and colleagues. The researchers concluded: ... tissue, isolated mice subsequently developed a significantly larger mammary gland tumors burden compared with group-housed mice. Endocrine evaluation confirmed that isolated mice ...
2009 NOV 16 ... decreased, the authors conclude. Current screening programs are leading to "potential tumor over-detection and over-treatment," they write in the Oct. 21, 2009 issue of JAMA. ... identify less aggressive interventions for minimal-risk disease to reduce treatment burden for patients and society." The authors list four recommendations in their ...
2009 NOV 23 ... not delay cancer treatment." Researchers used the Stanford Cancer Center tumor registry to retrospectively identify 82 women younger than 40 years old who received ... in vitro fertilization have benefited young women with breast cancer. "The burden of facing premature menopause adds to the stress experienced by young cancer ...
2009 NOV 16 ... scintigraphy and computer tomography (CT)/magnetic resonance imaging (MRI) for tumor localization in patients with catecholamine excess," scientists writing in the Journal ... and uptake of F-18-DOPA with PET were measured to determine the whole-body metabolic burden and correlated with biochemical tumor activity. The gold standard was a composite ...
2009 NOV 16 ... "Cathepsin S is a cysteine protease that promotes the invasion of tumor and endothelial cells during cancer progression. Here we investigated the potential to ... of tumor growth and neovascularization of HCT116 xenograft tumors," wrote R.E. Burden and colleagues, Queen's University. The researchers concluded: "These ...
2009 NOV 23 ... (IFN-gamma) assay in the detection of latent tuberculosis (TB) infection during tumor necrosis factor (TNF) antagonist treatment in Korean patients with initial negative TST ... diseases during longterm anti-TNF therapy, especially in areas with intermediate TB burden. (First Release Sept 1 2009; J Rheumatol 2009;36;2158-63; doi:10.3899/jrheuni.090150)." ...
2009 NOV 2 ... P = 0.002) and inversely with plasma homocysteine concentrations (r = -0.32; P = 0.005). Tumor burden was positively correlated with dietary folic acid levels (r = 0.35; P = 0.001) and ...
2009 NOV 16 ... of the 32 patients with a postbaseline scan (59%) had at least some reduction in overall tumor burden (median, 32%; range, 3-73%). The combination of sunitinib and bevacizumab in patients ...
2009 NOV 9 ... were examined. and hospitals were geocoded. Annual hospital procedure volume for each tumor site was examined, and multiple quantile and logistic regressions were used to compare ... increasingly centralized and that this centralization has resulted in increased travel burden for patients." "Using 1996 to 2006 discharge data from NY, NJ, PA, all ...
2009 NOV 16 ... is a potential new tool for immunotherapy of tumors that could be exploited to reduce tumor burden by controlling the traffic of Gr-1(+)CD11b(+) myeloid cells. [Cancer Res ...
2009 NOV 23 ... man with a history of asbestos exposure. The peritoneum was thickened with diffuse tumor proliferation. This patient was diagnosed as having malignant peritoneal epithelioid ... detail in 'Malignant peritoneal mesothelioma: quantitative analysis of asbestos burden,' new data in mesothelioma. According to recent research from Chiba, Japan, "Malignant ...
2009 NOV 23 ... PTX was administered before vandetanib. The combination of PTX plus vandetanib reduced tumor burden in the peritoneal cavity of mice and significantly increased their survival," wrote M. ...
2009 NOV 23 ... regimen of aerosolized a-TEA (36 mu g/mouset/treatment) significantly decreased primary tumor burden when compared to untreated or liposome control groups and was significantly better than ...
2009 NOV 9 ... study suggests that imatinib 400 mg twice a day results in more rapid reduction in tumor burden than imatinib 400 mg/d with minimal added toxicity." Cortes and colleagues ...
2009 NOV 23 ... an SDHB gene mutation. Here, we present an SDHB-related PHEO/PGL patient with extensive tumor burden, numerous organ lesions, and rapidly growing tumors, which responded extremely well to ...
2009 NOV 2 ... toxic, and cumbersome. Partly secondary to biases regarding the relative toxicities of tumor burden vs. treatment effect, therapy remains highly individualized," wrote E.M Dunbar and ...
2009 NOV 23 ... of TP53 mutations was statistically significantly associated with duration of smoking, tumor histology and gender. Smokers had approximately twice as high bulky adduct level as the ... The researchers concluded: "Our study provides evidence for a high burden of molecular alterations occurring concurrently in the lung of lung cancer patients." ...
