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2009 NOV 30 ... For nongenotoxic compounds, results showed that cellular changes indicative of a tumorigenic endpoint can be identified for many, but not all, of the chemicals producing tumors in ...
2009 NOV 23 ... researchers concluded: "Since our NPs selectively deliver both heat and drug to tumorigenic regions, they may improve the therapeutic effectiveness with minimal side ...
2009 NOV 30 ... multimolecular coagulation complexes assembly. Notably, Ixolaris inhibited the in vivo tumorigenic potential of U87-MG cells in nude mice, without observable bleeding. This inhibitory ...
2009 NOV 16 ... manner providing strong evidence that p53 exhibits both tumor suppressive and tumorigenic functions," scientists writing in the journal Biological Chemistry report. ...
2009 NOV 16 ... potential to target cathepsin S using an antagonistic antibody, Fsn0503, to block these tumorigenic effects," scientists in North Ireland report. "A panel of monoclonal ...
2009 NOV 30 ... that malignant tumors contain cancer-initiating cells (CIC), which self-renew and are tumorigenic. However, CICs have not been characterized Properly due to lack of specific markers." ...
2009 NOV 16 ... Harvard University, Medical Department. The researchers concluded: "Tumorigenic mutant p53 disrupts this circuit and makes cells more tolerable to stresses, as its ...
2009 NOV 16 ... nonsmall cell lung cancer (NSCLC) compared with normal lung tissue and has higher tumorigenic potential in SCID mice and expression of genes involved in stemness, adhesion, motility, ...
2009 NOV 16 ... and migration. Moreover, PSMA7 depletion was able to strongly suppress the in vivo tumorigenic ability of RKO cells. These effects may be induced by inhibiting CD44 expression ...
2009 NOV 30 ... report. "Using keratinocytes, we show here that partially transformed and tumorigenic cells systematically and spontaneously emerge from senescent cultures. We show that ...
2009 NOV 16 ... "The coordinated activation of FBP-1 and FBP-2 represents a novel and frequent pro-tumorigenic mechanism promoting proliferation (tumor growth) and motility (dissemination) of human ...
2009 NOV 16 ... the same amount of tumor cells without non-adherent spheroid selection remained non-tumorigenic. Sternness properties of these spheroid cells were further established by reverse ...
2009 NOV 30 ... research from Osaka, Japan, "ERas is a recently identified oncogene that supports the tumorigenic growth of embryonic stem cells, it is constitutively active in the absence of mutation. ...
2009 NOV 23 ... The dominant nature of BRAF(V600E) is evident by its ability to render Caco-2 cells tumorigenic in vivo all be it through selective extracellular signal-related kinase (ERK) 2 ...
2009 NOV 9 ... p73 splice forms (Delta TAp73) and Delta Np73 (summarized as DNp73) in the tumorigenic process, we designed locked nucleic acid (LNA) antisense oligonucleotide (ASO) gapmers ...
2009 NOV 16 ... and used it to demonstrate that loss of alpha-catenin resulted in increased in vitro tumorigenic characteristics (increased soft agarose colony formation, clonogenic survival after ...
2009 NOV 9 ... a group of lipophillic plant compounds that can have estrogenic effects in animals; both tumorigenic and anti-tumorigenic effects have been reported. ...
2009 NOV 30 ... GFP fluorescence intensity. In tumor-bearing mice, despite the very high frequency of tumorigenic cells, we successfully identified the NS-GFP(+) cells as tumor-initiating cells (T-ICs). ...
